Ronin samurai Ogami Itto and his young son Daigoro travel a dark road, beset by enemies sworn to destroy them. Ogami’s relentless quest for retribution takes him face to face with the sons of the war-bell warden, legions of organized crime bosses, a mysterious tattooed woman, a bounty-hunting gang who seek to enact their own vengeance, and a master gunsmith. And the Yagyu clan, fearful of the growing legend surrounding Lone Wolf, has decided to protect itself by sending its own assassin after him, and later pit the greatest swordsman of a rival clan against him.